Cdc25 is a dual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant. As with other cell cycle...
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CDC25 can refer to: Cdc25, a cell division cycle protein Another name for ras-GRF1, a guanine nucleotide exchange factor This disambiguation page lists...
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site. The effects of Wee1 and Myt1 are counteracted by phosphatases in the cdc25 family, which remove the inhibitory phosphates on CDK1 and thus convert...
22 KB (2,818 words) - 07:39, 3 June 2024
substrates. The CDC25 homology domain, also called the RasGEF domain, is the catalytic domain of many Ras GEFs, which activate Ras GTPases. The CDC25 domain comprises...
18 KB (2,253 words) - 09:08, 21 October 2023
dephosphorylation. CDC25 removes a phosphate from residues Threonine-14 (Thr-14) and Tyrosine-15 (Tyr-15) and adds a hydroxyl group. Cyclin B/CDK1 activates CDC25 resulting...
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CyclinB-Cdc2 activates the phosphatase Cdc25 which in turn deactivates the CyclinB-Cdc2 inhibitors, Wee1 and Myt1. Cdc25 activates the complex through the...
18 KB (2,233 words) - 13:06, 29 October 2024
additional function of Plk1 is to activate Cdc25 through phosphorylation. The compound effect of Wee1 degradation and Cdc25 activation is the net removal of inhibitory...
34 KB (4,581 words) - 15:21, 9 December 2024
families such as: PI3 Kinase, Ras GTPase-activating protein, CDC24 and cdc25. SH3 domains are found in proteins of signaling pathways regulating the...
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cell division cycle 25 homolog A (CDC25A) gene. CDC25A is a member of the CDC25 family of dual-specificity phosphatases. Dual-specificity protein phosphatases...
14 KB (1,642 words) - 16:33, 13 October 2024
p19) cip/kip (p21, p27, p57) P53 p63 p73 family p53 p63 p73 Other Cdc2 Cdc25 Cdc42 Cellular apoptosis susceptibility protein E2F Maturation promoting...
41 KB (4,735 words) - 04:45, 17 December 2024