Chemical chaperones are a class of small molecules that function to enhance the folding and/or stability of proteins. Chemical chaperones are a broad...
11 KB (1,382 words) - 20:45, 8 January 2024
In molecular biology, molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein...
29 KB (3,499 words) - 07:16, 20 February 2024
Sodium phenylbutyrate (section Chemical chaperone)
Sodium phenylbutyrate is also a histone deacetylase inhibitor and chemical chaperone, leading respectively to research into its use as an anti-cancer agent...
18 KB (1,661 words) - 05:42, 10 April 2024
of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution". Proceedings of the National Academy of Sciences...
46 KB (4,764 words) - 05:47, 1 October 2024
Sodium phenylbutyrate/ursodoxicoltaurine (category Chemical articles without CAS registry number)
mitochondria and in the endoplasmic reticulum. Sodium phenylbutyrate is a chemical chaperone that helps proteins maintain their normal conformation, preventing...
20 KB (1,270 words) - 21:00, 21 June 2024
Ursodoxicoltaurine (category Articles containing unverified chemical infoboxes)
S1PR2 and α5β1-Integrin. Tauroursodeoxycholic acid also acts as a chemical chaperone to help maintain the stability and correct folding of proteins. Ursodoxicoltaurine...
16 KB (1,569 words) - 20:20, 11 October 2024
GLA (gene) (category Chemical articles without CAS registry number)
pharmacological chaperone therapy.[citation needed] It has been shown that more potent competitive inhibitors of an enzyme can act as a more powerful chemical chaperone...
20 KB (1,933 words) - 01:32, 5 September 2024
of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution". Proceedings of the National Academy of Sciences...
15 KB (1,576 words) - 21:26, 5 November 2024
The chaperone code refers to post-translational modifications of molecular chaperones that control protein folding. Whilst the genetic code specifies...
11 KB (1,312 words) - 23:12, 3 December 2023
Chaperone-mediated autophagy (CMA) refers to the chaperone-dependent selection of soluble cytosolic proteins that are then targeted to lysosomes and directly...
31 KB (3,623 words) - 00:33, 22 June 2024