In computational chemistry, conformational ensembles, also known as structural ensembles, are experimentally constrained computational models describing...
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Protein structure (redirect from Protein conformation)
amounts of experimental data to the conformations which is a very computationally demanding task. The conformational ensembles were generated for a number of...
36 KB (4,022 words) - 16:54, 15 June 2024
modifications, protein interactions or alternative splicing modulate the conformational ensembles of fuzzy complexes, to fine-tune affinity or specificity of interactions...
25 KB (2,841 words) - 17:04, 19 May 2024
Allosteric enzymes are enzymes that change their conformational ensemble upon binding of an effector (allosteric modulator) which results in an apparent...
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study conformational flexibility of IDPs and the kinetics of structural transitions, optical tweezers for high-resolution insights into the ensembles of...
52 KB (6,004 words) - 15:08, 6 May 2024
are not strictly static objects, but rather populate ensembles of (sometimes similar) conformations. Transitions between these states occur on a variety...
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assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and movies can be created. Chimera includes...
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Klaus R. (2019). "Characterizing the Diversity of the CDR-H3 Loop Conformational Ensembles in Relationship to Antibody Binding Properties". Frontiers in Immunology...
16 KB (2,062 words) - 20:27, 22 July 2024
Savir Y, Tlusty T (May 2007). Scalas E (ed.). "Conformational proofreading: the impact of conformational changes on the specificity of molecular recognition"...
96 KB (9,819 words) - 12:03, 26 July 2024
the induced fit model, and the conformational selection model. The latter two are not mutually exclusive: conformational selection can be followed by a...
41 KB (4,859 words) - 20:41, 22 July 2024