DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role...
23 KB (2,787 words) - 00:53, 18 June 2024
Ligation (molecular biology) (redirect from DNA ligation)
procedures for ligation without the use of standard DNA ligase are also popular. Human DNA ligases abnormalities have been linked to pathological disorders...
36 KB (4,679 words) - 19:39, 16 August 2024
ligases include the word "ligase", such as in DNA ligase, an enzyme commonly used in molecular biology laboratories to join together DNA fragments. However,...
4 KB (430 words) - 15:26, 14 July 2024
DNA ligase 1 also DNA ligase I, is an enzyme that in humans is encoded by the LIG1 gene. DNA ligase 1 is the only known eukaryotic DNA ligase involved...
23 KB (2,878 words) - 08:09, 5 August 2024
DNA ligase 4 also DNA ligase IV, is an enzyme that in humans is encoded by the LIG4 gene. DNA ligase 4 is an ATP-dependent DNA ligase that joins double-strand...
15 KB (1,821 words) - 05:44, 11 June 2024
Okazaki fragments (category DNA replication)
discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication. They were discovered in the 1960s by...
33 KB (4,435 words) - 14:24, 7 June 2024
Molecular cloning (redirect from Recombinant DNA technology)
enzyme, DNA ligase, fragments generated by restriction enzymes could be joined in new combinations, termed recombinant DNA. By recombining DNA segments...
32 KB (4,016 words) - 17:56, 20 August 2024
capable of recognizing nicks in DNA. The ligase forms a DNA-adenylate complex, assisting recognition. With human DNA ligase, this forms a crystallized complex...
16 KB (2,041 words) - 14:01, 2 July 2024
DNA ligase 3 also DNA ligase III, is an enzyme that, in humans, is encoded by the LIG3 gene. LIG3 encodes ATP-dependent DNA ligases that seal interruptions...
30 KB (3,749 words) - 18:26, 16 August 2024
Natural competence (section Mechanisms of DNA uptake)
is the ability of a cell to alter its genetics by taking up extracellular DNA from its environment through a process called transformation. Competence...
17 KB (1,906 words) - 03:36, 5 August 2024