Histone deacetylase 5 is an enzyme that in humans is encoded by the HDAC5 gene. Histones play a critical role in transcriptional regulation, cell cycle...
17 KB (1,862 words) - 05:58, 6 December 2023
Histone deacetylases (EC 3.5.1.98, HDAC) are a class of enzymes that remove acetyl groups (O=C-CH3) from an ε-N-acetyl lysine amino acid on both histone...
31 KB (3,181 words) - 07:12, 12 August 2024
Histone deacetylase inhibitors (HDAC inhibitors, HDACi, HDIs) are chemical compounds that inhibit histone deacetylases. Since deacetylation of histones...
26 KB (2,974 words) - 05:26, 31 May 2024
Histone deacetylase 2 (HDAC2) is an enzyme that in humans is encoded by the HDAC2 gene. It belongs to the histone deacetylase class of enzymes responsible...
41 KB (4,587 words) - 20:20, 3 December 2023
HDAC3 (redirect from Histone deacetylase 3)
Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice. Histones are highly alkaline proteins that package and order DNA...
22 KB (2,493 words) - 10:39, 27 December 2023
catalysed by enzymes with "histone acetyltransferase" (HAT) or "histone deacetylase" (HDAC) activity. Acetylation is the process where an acetyl functional...
58 KB (7,036 words) - 21:48, 28 February 2024
HDAC6 (redirect from Histone deacetylase 6)
Histone deacetylase 6 is an enzyme that in humans is encoded by the HDAC6 gene. HDAC6 has emerged as a highly promising candidate to selectively inhibit...
15 KB (1,738 words) - 07:16, 11 March 2024
HDAC1 (redirect from Histone deacetylase 1)
Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene. Histone acetylation and deacetylation, catalyzed by multisubunit...
50 KB (5,476 words) - 01:27, 4 January 2024
Genetics Histone acetyltransferase Histone deacetylases Histone methyltransferase Histone-modifying enzymes Nucleosome PRMT4 pathway Protamine Histone H1 Youngson...
84 KB (9,582 words) - 18:07, 20 August 2024
Vorinostat (category Histone deacetylase inhibitors)
member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic...
17 KB (1,442 words) - 05:28, 7 May 2024