also known as LAG-3, is a protein which in humans is encoded by the LAG3 gene. LAG3, which was discovered in 1990 and was designated CD223 (cluster of...

inhibitory receptor Lymphocyte-Activation Gene 3 (LAG3), yielding insights, notably demonstrating the role of LAG3 in regulating Treg activity and function. His...

company working primarily in the field of cancer immunotherapy using the LAG3 immune control mechanism. The company was originally built on CVac, a therapeutic...

is a French immunologist who is best known for his 1990 discovery of the LAG3 immune control mechanism. Triebel worked through the 1990s in a collaboration...

immune system. In tumors Th3 cells can express lymphocyte activation gene-3 (LAG3). Th3 cells produce vast amounts of TGF-β and to a lesser degree also the...

Bristol-Myers Squibb is working on Lirilumab, a monoclonal antibody to KIR. LAG3: short for Lymphocyte Activation Gene-3, works to suppress an immune response...

receptor binding domain (RBD) of SARS-CoV-2 Y COVID-19 Relatlimab mab human LAG3 melanoma Remtolumab mab human IL-17A, TNF Reslizumab Cinqair mab humanized...

HGNC:18512 Q53H82 8524 LACTBL1 HGNC:35445 A8MY62 8525 LAD1 HGNC:6472 O00515 8526 LAG3 HGNC:6476 P18627 8527 LAGE3 HGNC:26058 Q14657 8528 LAIR1 HGNC:6477 Q6GTX8...

anti-PD-1 and PD-L1 drugs in combination with other immunotherapy drugs blocking LAG3, B7-H3, KIR, OX40, PARP, CD27, and ICOS. Pembrolizumab (Keytruda, formerly...

cell membrane protein-3 (TIM3), and lymphocyte activation gene 3 protein (LAG3). Soluble molecules such as cytokines IL-10 or TGF-β are also able to trigger...