The recombination-activating genes (RAGs) encode parts of a protein complex that plays important roles in the rearrangement and recombination of the genes...

recombination is mediated by VDJ recombinase, which is a diverse collection of enzymes. The key enzymes involved are recombination activating genes 1...

Recombination activating gene 2 protein (also known as RAG-2) is a lymphocyte-specific protein encoded by the RAG2 gene on human chromosome 11. Together...

Recombination activating gene 1 also known as RAG-1 is a protein that in humans is encoded by the RAG1 gene. The RAG1 and RAG2 genes are largely conserved...

designed to manipulate the gene under study and the other recombination event is necessary for activating a reporter gene (usually encoding a fluorescent...

missense mutations in immunologically relevant genes of T-cells (and B-cells) such as recombination activating genes (RAG1 and RAG2), Interleukin-7 receptor-α...

inactivation of a specific gene within an organism's genome. This can be done through a variety of methods, including homologous recombination, CRISPR-Cas9, and...

to adapt during the course of evolution. Homologous recombination is also used in horizontal gene transfer to exchange genetic material between different...

Generation of junctional diversity starts as the proteins, recombination activating gene-1 and -2 (RAG1 and RAG2), along with DNA repair proteins, such...

asynchronous recombination models, the recombination process is controlled by timing of recombination-activating gene (RAG) recombinase and accessibility...