transporter), member 12, also known as SLC22A12 and URAT1, is a protein which in humans is encoded by the SLC22A12 gene. The protein encoded by this gene...
9 KB (1,079 words) - 11:05, 18 July 2024
reabsorption inhibitor that has uric acid lowering activity by inhibiting URAT1/SLC22A12 receptor. It is a structural analog of Benzbromarone. Kuriyama S (March...
5 KB (251 words) - 15:30, 1 February 2024
contributing to about 60% of variability in uric acid level. The SLC2A9, SLC22A12, and ABCG2 genes have been found to be commonly associated with gout and...
83 KB (8,329 words) - 00:15, 19 October 2024
Losartan is a uricosuric. As a specific inhibitor of the urate transporter 1 (SLC22A12, URAT1), losartan blocks the uptake of uric acid into cells, thus leaving...
41 KB (3,269 words) - 22:06, 30 August 2024
urate, have so far been identified: SLC2A9; ABCG2; SLC17A1; SLC22A11; SLC22A12; SLC16A9; GCKR; LRRC16A; and PDZK1. GLUT9, encoded by the SLC2A9 gene,...
39 KB (3,928 words) - 13:56, 15 October 2024
act in vitro by blocking the function of a protein encoded by the gene SLC22A12, also known as urate transporter 1 or URAT1. URAT1 is the central mediator...
7 KB (858 words) - 19:53, 22 September 2024
SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A7 SLC22A8 SLC22A9 SLC22A10 SLC22A11 SLC22A12 SLC22A13 SLC22A14 SLC22A15 SLC22A16 SLC22A17 SLC22A18 SLC22A19 SLC22A20...
31 KB (3,438 words) - 05:47, 22 August 2024
SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A7 SLC22A8 SLC22A9 SLC22A10 SLC22A11 SLC22A12 SLC22A13 SLC22A14 SLC22A15 SLC22A16 SLC22A17 SLC22A18 SLC22A19 SLC22A20...
13 KB (1,671 words) - 11:59, 5 October 2024
SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A7 SLC22A8 SLC22A9 SLC22A10 SLC22A11 SLC22A12 SLC22A13 SLC22A14 SLC22A15 SLC22A16 SLC22A17 SLC22A18 SLC22A19 SLC22A20...
16 KB (1,327 words) - 21:12, 2 October 2024
T, Hosoya T (September 2008). "Age and origin of the G774A mutation in SLC22A12 causing renal hypouricemia in Japanese". Clin. Genet. 74 (3): 243–51. doi:10...
13 KB (1,438 words) - 04:56, 14 August 2024