transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene. It is a member of the STAT protein family. STAT3 is a member...
29 KB (3,481 words) - 17:50, 29 August 2024
STAT3 gain-of function (GOF) is a rare genetic disorder of the immune system, leading to early-onset autoimmunity and a variety of multi-organ disorders...
14 KB (1,528 words) - 03:45, 8 April 2024
between PI3K and JAK in Stat3 phosphorylation is that PI3K phosphorylates Stat3 on the S727 residue whereas JAK phosphorylates Stat3 on the Y705 residue....
31 KB (2,895 words) - 01:46, 5 August 2024
phosphate groups to) proteins. There are seven STAT proteins: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6. STAT proteins contain many different domains...
62 KB (6,845 words) - 18:30, 22 August 2024
Protein acetylation (section STAT3)
nucleus. STAT3 regulates several genes in response to growth factors and cytokines and play an important role in cell growth. Therefore, STAT3 facilitates...
42 KB (4,895 words) - 08:33, 15 January 2024
dominant or autosomal recessive. Many patients with autosomal dominant STAT3 hyper-IgE syndrome have characteristic facial and dental abnormalities,...
17 KB (1,502 words) - 04:08, 17 March 2024
STAT protein (redirect from STAT3 gene)
mammalian STAT family members that have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6. STAT1 homodimers are involved...
6 KB (514 words) - 21:03, 25 November 2022
Nifuroxazide (section STAT3 inhibition)
antibiotic activity, nifuroxazide has been found to be a potent inhibitor of STAT3, and consequently has been proposed as a cancer treatment. High aldehyde...
6 KB (444 words) - 12:54, 30 March 2024
National Medical Center in Duarte, California. His research has shown that the STAT3 protein plays a role in protecting cancers from immune responses and contributes...
14 KB (1,070 words) - 15:11, 4 January 2024
STAT3 (pSTAT3), found in 50% of lung adenocarcinomas, and IL-6. Further investigation revealed that mutant EGFR could activate the oncogenic STAT3 pathway...
18 KB (2,105 words) - 01:40, 20 August 2024