amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene. TAAR1 is an intracellular...

monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons...

norepinephrine release in TAAR1 knockout mice. In fact, TAAR1 knockout mice are supersensitive to the effects of amphetamines and TAAR1 activation appears to...

changes. It can also weakly activate the trace amine-associated receptor, TAAR1 (hTAAR1 in humans). Limited studies have considered tryptamine to be a trace...

amine-assorted receptor 1 (TAAR1), a G-Coupled Protein Receptor GPCR, to regulate monoaminergic systems in the brain. Active TAAR1 opposes the autoreceptor's...

its parent compound, amphetamine, as they both are TAAR1 agonists, where the activation of TAAR1 in monoamine neurons facilitates the efflux, or release...

has been shown to activate TAAR1 in human astrocytes and generate cAMP as a result. Activation of astrocyte-localized TAAR1 appears to function as a mechanism...

tyramine, called TAAR1. The TAAR1 receptor is found in the brain, as well as peripheral tissues, including the kidneys. Tyramine binds to TAAR1 as an agonist...

Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally...

and dopamine in the brain. Solriamfetol has also been found to act as a TAAR1 agonist, an action that may also be involved in its effects. The drug was...