• Thumbnail for Tezacaftor
    Tezacaftor is a drug used for the treatment of cystic fibrosis (CF) in people six years and older, who have a F508del mutation, the most common type of...
    11 KB (724 words) - 19:14, 30 November 2023
  • Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta and Kaftrio, is a fixed-dose combination medication used to treat cystic fibrosis...
    38 KB (3,107 words) - 08:02, 24 June 2024
  • Thumbnail for Ivacaftor
    in combination medications, lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic...
    34 KB (3,157 words) - 19:11, 14 June 2024
  • Thumbnail for Elexacaftor
    available in a single pill with ivacaftor and tezacaftor; the fixed-dose combination, elexacaftor/tezacaftor/ivacaftor (brand name Trikafta), is used to...
    7 KB (286 words) - 14:34, 17 May 2024
  • Thumbnail for Vertex Pharmaceuticals
    2017, Vertex announced Phase 3 data from a dual combination treatment, tezacaftor plus ivacaftor, in patients with cystic fibrosis. On 12 February 2018...
    37 KB (3,628 words) - 05:20, 13 September 2024
  • Thumbnail for Cystic fibrosis
    approved the combination ivacaftor/tezacaftor; the manufacturer announced a list price of $292,000 per year. Tezacaftor helps move the CFTR protein to the...
    161 KB (18,074 words) - 10:17, 8 September 2024
  • R07AX30 Ivacaftor and lumacaftor R07AX31 Ivacaftor and tezacaftor R07AX32 Ivacaftor, tezacaftor and elexacaftor "ATC (Anatomical Therapeutic Chemical Classification...
    1,000 bytes (237 words) - 06:04, 4 January 2021
  • endometrial carcinoma Lenvatinib Eisai endometrial carcinoma Elexacaftor/tezacaftor/ivacaftor Vertex Pharmaceuticals cystic fibrosis Zanubrutinib BeiGene...
    34 KB (180 words) - 22:09, 8 April 2024
  • (~ 50% of CF patients). Most recently, Grootenhuis's team discovered Tezacaftor (VX-661) and Elexacaftor (VX-445), which in combination with Ivacaftor...
    10 KB (964 words) - 21:17, 14 September 2024
  • Thumbnail for Cystic fibrosis and race
    CFTR modulators for specific mutations. One such drug is elexacaftor/tezacaftor/ivacaftor. However, the cost of CFTR modulators is high. In addition to...
    34 KB (3,174 words) - 07:09, 22 June 2024