• Alirocumab, sold under the brand name Praluent, is a medication used as a second-line treatment for high cholesterol for adults whose cholesterol is not...
    24 KB (2,254 words) - 05:22, 7 April 2024
  • Regeneron's drug alirocumab infringed Amgen's patents; Amgen then requested an injunction barring Regeneron and Sanofi from marketing alirocumab, which was...
    17 KB (1,472 words) - 06:49, 29 June 2024
  • Thumbnail for PCSK9
    can lower LDL particle concentrations. The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injections, by the...
    69 KB (7,354 words) - 16:56, 11 June 2024
  • Thumbnail for Regeneron Pharmaceuticals
    metastatic colorectal cancer approved by the FDA in August 2012. Praluent (alirocumab) is indicated as an adjunct to diet and maximally tolerated statin therapy...
    26 KB (2,282 words) - 07:41, 31 August 2024
  • Thumbnail for Hypercholesterolemia
    Injectable antibodies against the protein PCSK9 (evolocumab, bococizumab, alirocumab) can reduce LDL cholesterol and have been shown to reduce mortality. In...
    61 KB (6,215 words) - 17:45, 31 May 2024
  • 2024 MA 2001 Valdecoxib 2016 N/A SM 2001 Etoricoxib 2016 N/A SM 2003 Alirocumab 2015 2035 MA 2006 Linagliptin 2011 2031 SM 2007 Apixaban 2012 2032 SM...
    34 KB (2,388 words) - 06:34, 15 August 2024
  • (Clopidogrel), for atherothrombosis, marketed by Bristol-Myers Squibb. Praluent (Alirocumab), for heterozygous familial hypercholesterolemia and clinical atherosclerotic...
    91 KB (8,778 words) - 06:05, 10 August 2024
  • Thumbnail for List of therapeutic monoclonal antibodies
    Alemtuzumab Lemtrada, Campath mab humanized CD52 Y multiple sclerosis Alirocumab Praluent mab human PCSK9 Y hypercholesterolemia Altumomab pentetate Hybri-ceaker...
    136 KB (4,020 words) - 07:14, 15 August 2024
  • Thumbnail for Familial hypercholesterolemia
    importance of early identification of FH and treatment with statins. Alirocumab and evolocumab, both monoclonal antibodies against PCSK9, are specifically...
    48 KB (5,456 words) - 18:52, 29 May 2024
  • Thumbnail for Monoclonal antibody therapy
    intravenous humanized CD52 B-cell chronic lymphocytic leukemia 103948 Link alirocumab Praluent Sanofi Aventis 7/24/2015 subcutaneous fully human PCSK9 Heterozygous...
    57 KB (4,072 words) - 11:12, 5 August 2024