Cullin-4B is a protein that in humans is encoded by the CUL4B gene which is located on the X chromosome. CUL4B has high sequence similarity with CUL4A, with which...
23 KB (2,948 words) - 23:56, 9 September 2023
larger subunit DDB1 primarily functions as a core component of CUL4A- and CUL4B-based E3 ubiquitin ligase complexes. Substrates that are ubiquitinnated...
31 KB (3,001 words) - 07:13, 14 August 2024
humans is encoded by the DCAF15 gene. DCAF15 forms a complex with CUL4A or CUL4B that has E3 ubiquitin ligase activity and is responsible for the proteasome...
965 bytes (144 words) - 06:15, 28 March 2022
HGNC:2552 Q13617 3792 CUL3 HGNC:2553 Q13618 3793 CUL4A HGNC:2554 Q13619 3794 CUL4B HGNC:2555 Q13620 3795 CUL5 HGNC:2556 Q93034 3796 CUL7 HGNC:21024 Q14999...
277 KB (17 words) - 19:37, 1 October 2024
found that DDB1 primarily functions as a core component of the CUL4A- and CUL4B-based E3 ubiquitin ligase complexes. DDB1 serves as a bridge or adaptor...
12 KB (1,415 words) - 16:33, 23 December 2023
cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin...
36 KB (4,418 words) - 03:28, 3 December 2023
complex (Elongin C - CUL2 - SOCS-box) CUL3, part of CUL3-BTB complex CUL4A CUL4B CUL5 CUL7 CUL9, also known as PARC There is also a more distant member called...
7 KB (718 words) - 21:57, 20 September 2023
protein-containing complex binding Cellular component nucleoplasm cell junction Cul4B-RING E3 ubiquitin ligase complex nucleus Cul4-RING E3 ubiquitin ligase complex...
16 KB (2,071 words) - 18:17, 2 October 2024
microtubule organizing center nucleolus Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex cytoskeleton nucleus nucleoplasm cytoplasm...
4 KB (486 words) - 21:43, 20 February 2024
Cul7-RING ubiquitin ligase complex Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex nucleus nucleoplasm nuclear SCF ubiquitin...
13 KB (1,550 words) - 01:52, 11 April 2024