There are three isoforms of CXCR3 in humans: CXCR3-A, CXCR3-B and chemokine receptor 3-alternative (CXCR3-alt). CXCR3-A binds to the CXC chemokines...
19 KB (2,235 words) - 16:33, 19 August 2023
CXCL9 (section CXCL9/CXCR3 and the PDL-1/PD-1)
multiplication of leukocytes, and cause tissue extravasation. The CXCL9/CXCR3 receptor regulates immune cell migration, differentiation, and activation...
21 KB (2,612 words) - 11:46, 29 July 2024
CXC chemokine receptors (section CXCR3)
highly induced following cell activation. There are two isoforms, CXCR3-A and CXCR3-B. It has three highly related ligands in mammals, CXCL9, CXCL10 and...
9 KB (885 words) - 07:16, 30 April 2024
and interacts with a splice variant of the chemokine receptor CXCR3, known as CXCR3-B. The heparin:PF4 complex is the antigen in heparin-induced thrombocytopenia...
14 KB (1,641 words) - 10:51, 29 July 2024
its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9...
13 KB (1,725 words) - 11:52, 29 July 2024
chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. The three-dimensional crystal structure of this chemokine has been determined...
10 KB (1,231 words) - 22:00, 8 March 2024
the site of inflammation are: CCL2, CCL1, CCL22 and CCL17. Furthermore, CXCR3 expression by T-cells is induced following T-cell activation and activated...
30 KB (2,931 words) - 10:43, 29 July 2024
is required for both interferon gamma and cytolytic potential. CCR5 and CXCR3 are the main chemokine receptors for this cell. Group 1 ILCs Groups 1 ILCs...
14 KB (1,381 words) - 19:57, 18 August 2024
case, CCL21 binds to C-C chemokine receptor type 7 and chemokine receptor CXCR3 receptors on microglia in the thalamus. The physiologic response to the...
16 KB (1,878 words) - 21:23, 17 July 2024
diseases. One way in which intestinal permeability is modulated is via CXCR3 receptors in cells in the intestinal epithelium, which respond to zonulin...
26 KB (2,844 words) - 07:42, 22 June 2024