enzymology, a ceramide kinase, also abbreviated as CERK, (EC 2.7.1.138) is an enzyme that catalyzes the chemical reaction: ATP + ceramide ⇌ {\displaystyle...
16 KB (1,895 words) - 19:02, 3 November 2024
Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid joined by an amide bond. Ceramides are found in...
30 KB (3,361 words) - 11:32, 4 November 2024
Lipid signaling (section Ceramide)
be attached to ceramide (phosphorylation) by the enzyme, ceramide kinase. It is also possible to regenerate sphingomyelin from ceramide by accepting a...
55 KB (5,633 words) - 08:40, 12 July 2024
subsequently has several fates. It may be phosphorylated by ceramide kinase to form ceramide-1-phosphate. Alternatively, it may be glycosylated by glucosylceramide...
25 KB (2,774 words) - 16:47, 24 September 2024
OSH1 and YHR073w. Ceramide kinase, a lipid kinase that phosphorylates ceramides to ceramide-1-phosphate. G protein receptor kinases (GRK) of GRK2 subfamily...
14 KB (1,434 words) - 18:03, 6 October 2024
"Cannabinoids protect astrocytes from ceramide-induced apoptosis through the phosphatidylinositol 3-kinase/protein kinase B pathway". The Journal of Biological...
32 KB (3,463 words) - 17:34, 20 November 2023
energy sensor" AMP-activated protein kinase (AMPK), the O-GlcNAc transferase enzyme (OGT), and the pro-apoptotic kinase ROCK1. RNA phase transitions driven...
183 KB (12,460 words) - 13:46, 23 September 2024
(sphinganine), acylated to dihydroceramide and finally oxidized by FAD to ceramide. Sphingosine is then solely formed via degradation of sphingolipid in the...
4 KB (220 words) - 20:12, 19 July 2024
Ceramide-activated protein phosphatases (CAPPs) are a group of enzymes that are activated by the lipid second messenger ceramide. Known CAPPs include members...
18 KB (2,665 words) - 02:19, 4 September 2024
Van Veldhoven PP (Feb 2006). "Further characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and...
11 KB (1,381 words) - 06:22, 10 June 2024