Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface molecule encoded by the B locus in the major histocompatibility complex (MHC)...
16 KB (1,516 words) - 09:54, 16 February 2024
spondylitis: A version of the HLA-B gene called HLA-B27 increases the risk of developing ankylosing spondylitis. It is uncertain how HLA-B27 causes this increased...
17 KB (1,889 words) - 01:57, 10 March 2024
affected in the UK have a specific human leukocyte antigen known as the HLA-B27 antigen. The underlying mechanism is believed to be autoimmune or autoinflammatory...
56 KB (5,950 words) - 20:22, 8 July 2024
HLA-B27, which has important features: HLA-B27 AAU can be associated with ocular inflammation alone or in association with systemic disease. HLA-B27 AAU...
31 KB (3,207 words) - 19:48, 21 May 2024
Human leukocyte antigen (redirect from HLA antigen)
(e.g., HLA-B27 or, shortened, B27). A parallel system that allowed more refined definition of alleles was developed. In this system, an "HLA" is used...
51 KB (5,941 words) - 20:20, 27 June 2024
B27 may refer to: Bundesstraße 27, a German road HLA-B27, an HLA B serotype Mark 27 nuclear bomb Martin XB-27, a proposed experimental American aircraft...
252 bytes (71 words) - 20:01, 7 December 2021
seronegative spondylarthropathies. They have an increased incidence of HLA-B27, as well as negative rheumatoid factor and ANA. Enthesopathy is also sometimes...
12 KB (1,096 words) - 06:23, 23 June 2024
site has already improved). Reactive arthritis is an RF-seronegative, HLA-B27-linked arthritis often precipitated by genitourinary or gastrointestinal...
21 KB (2,292 words) - 09:56, 8 November 2023
Major histocompatibility complex (section HLA biology)
autoimmune diseases more than having others. HLA-B27 is an example. It is unclear how exactly having the HLA-B27 tissue type increases the risk of ankylosing...
57 KB (6,750 words) - 12:31, 15 July 2024
SUMO4 gene variant is involved, and symptoms appear to be milder when HLA-B27 is present. Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.;...
16 KB (960 words) - 01:10, 1 June 2024