Mipomersen (INN; trade name Kynamro) is a drug used to treat homozygous familial hypercholesterolemia and is administered by subcutaneous injection. There...
15 KB (786 words) - 10:17, 20 October 2023
targets. In 2008, Isis and Genzyme entered into a partnered drug candidate mipomersen (Kynamro), intended to treat homozygous familial hypercholesterolemia...
16 KB (1,425 words) - 21:53, 21 August 2024
Gapmer (section Mipomersen (Kynamro))
Corporation, is administered via subcutaneous injection in the form of a mipomersen sodium solution. The chemical structure is composed of a 20-nucleotide...
10 KB (1,142 words) - 05:31, 14 March 2024
example of using an asRNA as a therapeutic agent is mipomersen, which was approved by FDA in 2013. Mipomersen was developed to manage the level of low-density...
24 KB (2,997 words) - 00:53, 25 July 2024
phosphorothioate antisense oligonucleotides fomivirsen (Vitravene) and mipomersen (Kynamro) for human therapeutic use. In virology, the term "sense" has...
19 KB (2,444 words) - 17:30, 3 December 2023
a novel antioxidant, failed a phase-III trial. Apoprotein-B inhibitor mipomersen (approved by the FDA in 2013 homozygous familial hypercholesterolemia...
11 KB (1,251 words) - 17:11, 6 June 2024
treatment of familial chylomicronaemia syndrome in May 2019. In January 2013 mipomersen (marketed as Kynamro) was approved by the FDA for the treatment of homozygous...
23 KB (2,219 words) - 02:24, 20 August 2024
familial hypercholesterolemia. In January 2013, The US FDA also approved mipomersen, which inhibits the action of the gene apolipoprotein B, for the treatment...
48 KB (5,456 words) - 18:52, 29 May 2024
e.g., the drugs fomivirsen (Vitravene), Oblimersen, Alicaforsen, and Mipomersen (Kynamro). Further examples of these include: Diazinon Fenitrothion Fenthion...
5 KB (491 words) - 06:11, 7 November 2023
(Desirudin), for atherothrombosis, Now owned by Bausch Health. Kynamro (Mipomersen), an antisense drug invented by Isis Pharmaceuticals and acquired by Genzyme...
91 KB (8,778 words) - 06:05, 10 August 2024