and PANoptosis PANoptosis has also been implicated in inflammatory diseases, neurological diseases, and cancer. Additionally, activation of PANoptosis can...
41 KB (3,997 words) - 20:05, 13 August 2024
biological effects in PANoptosis cannot be individually accounted for by pyroptosis, apoptosis, or necroptosis alone. PANoptosis is regulated by multifaceted...
16 KB (1,853 words) - 22:59, 13 July 2024
Thirumala-Devi Kanneganti (section Discovery of NLRP3 inflammasome, ZBP1-, RIPK1-, AIM2-, and NLRP12-PANoptosomes, and PANoptosis as therapeutic targets for infectious and inflammatory diseases and cancer)
regulator of inflammation and cell death, regulates the activation of PANoptosis. PANoptosis is implicated in driving innate immune responses and inflammation...
44 KB (4,323 words) - 21:19, 29 July 2024
ZBP1-PANoptosome to activate the NLRP3 inflammasome and drive cell death, PANoptosis. PANoptosis is a prominent innate immune, inflammatory, and lytic cell death...
21 KB (2,538 words) - 04:31, 17 August 2024
which drive another distinct form of pro-inflammatory cell death called PANoptosis. The germline-encoded PRRs that drive inflammasome formation consist of...
71 KB (7,823 words) - 11:34, 29 July 2024
that, upon NAD+ depletion, forms a PANoptosome, driving PANoptosis and inflammation. PANoptosis is a prominent innate immune, inflammatory, and lytic cell...
8 KB (798 words) - 17:46, 15 August 2024
an innate immune sensor that triggers inflammatory cell death, PANoptosis. PANoptosis is a prominent innate immune, inflammatory, and lytic cell death...
21 KB (2,097 words) - 17:17, 16 August 2024
identified roles in programmed cell death such as pyroptosis, necroptosis and PANoptosis. These forms of cell death are important for protecting an organism from...
28 KB (3,113 words) - 05:35, 29 April 2024
of inflammatory cell death, which include pyroptosis, necroptosis, and PANoptosis. These cell death pathways help clear infected or aberrant cells and release...
43 KB (4,797 words) - 03:20, 11 July 2024
of larger cell death-inducing complexes called PANoptosomes to induce PANoptosis, another inflammatory form of cell death. Activated caspase-1 is responsible...
35 KB (3,948 words) - 06:00, 10 June 2024