• Pantothenate kinase (EC 2.7.1.33, PanK; CoaA) is the first enzyme in the Coenzyme A (CoA) biosynthetic pathway. It phosphorylates pantothenate (vitamin...
    21 KB (2,484 words) - 10:09, 19 May 2024
  • Pantothenate kinase-associated neurodegeneration (PKAN), formerly called Hallervorden–Spatz syndrome, is a genetic degenerative disease of the brain that...
    18 KB (2,034 words) - 11:07, 5 June 2024
  • Thumbnail for Pantothenic acid
    Pantothenic acid is phosphorylated to 4′-phosphopantothenate by the enzyme pantothenate kinase. This is the committed step in CoA biosynthesis and requires ATP...
    32 KB (3,266 words) - 02:34, 11 July 2024
  • Thumbnail for Neurofibrillary tangle
    panencephalitis As well as lead encephalopathy, tuberous sclerosis, Pantothenate kinase-associated neurodegeneration, and lipofuscinosis Proteopathy Alonso...
    25 KB (2,860 words) - 15:17, 20 June 2024
  • genetic conditions such as Huntington's disease, neuroacanthocytosis, pantothenate kinase-associated neurodegeneration, Duchenne muscular dystrophy, Wilson's...
    9 KB (528 words) - 16:10, 30 August 2021
  • Thumbnail for PANK2 (gene)
    Pantothenate kinase 2, mitochondrial is an enzyme that in humans is encoded by the PANK2 gene. This gene encodes a protein belonging to the pantothenate...
    7 KB (813 words) - 08:22, 11 December 2023
  • genetic conditions such as Huntington's disease, neuroacanthocytosis, pantothenate kinase-associated neurodegeneration, Duchenne muscular dystrophy, Wilson's...
    24 KB (2,502 words) - 19:39, 16 May 2024
  • Thumbnail for Chromosome 20
    prepropeptide PANK2: pantothenate kinase 2 (pantothenate kinase-associated neurodegeneration) PKIG: encoding protein cAMP-dependent protein kinase inhibitor gamma...
    22 KB (1,573 words) - 04:43, 27 December 2023
  • the discovery of Hallervorden-Spatz syndrome (now referred to as Pantothenate kinase-associated neurodegeneration). Hugo Spatz's Oberarzt (senior resident...
    2 KB (181 words) - 20:52, 20 April 2024
  • Thumbnail for Methylmalonic acidemias
    ME, et al. (January 2024). "Pantothenate Kinase Activation Restores Brain Coenzyme A in a Mouse Model of Pantothenate Kinase-Associated Neurodegeneration"...
    49 KB (4,433 words) - 18:08, 16 June 2024