Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of amyloid beta (Aβ) protein that present...

Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...

Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...

generates amyloid beta (Aβ), a polypeptide containing 37 to 49 amino acid residues, whose amyloid fibrillar form is the primary component of amyloid plaques found...

Notably, amyloid plaques have been hypothesized to counteract this BBB leakage. However, upon the administration of antibodies, these plaques are targeted...

and cingulate gyrus. Both amyloid plaques and neurofibrillary tangles are clearly visible by microscopy in AD brains. Plaques are dense, mostly insoluble...

of abnormally folded amyloid beta protein into amyloid plaques, and tau protein into neurofibrillary tangles in the brain. Plaques are made up of small...

as the first, primarily measuring the effectiveness on reducing amyloid brain plaques. The increase in dosage led to a larger percentage of participants...

several different types of amyloid. In almost all of the organ-specific pathologies, there is debate as to whether the amyloid plaques are the causal agent...

of atherosclerotic changes is similar to that in the development of amyloid plaques in the brain and that of age spots on the skin. Misrepair-accumulation...