regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes...
39 KB (4,535 words) - 10:15, 29 May 2024
Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. Aurora A is a member of a family...
22 KB (2,764 words) - 06:39, 6 May 2024
Aurora kinases are serine/threonine kinases that are essential for cell proliferation. They are phosphotransferase enzymes that help the dividing cell...
4 KB (535 words) - 20:14, 4 January 2024
member of the highly conserved Aurora subfamily of serine/threonine protein kinases with two other members, Aurora A and Aurora B. The encoded protein is a...
15 KB (1,969 words) - 23:57, 29 December 2023
Aurora kinase inhibitors are a putative drug class for treating cancer. The Aurora kinase enzymes could be potential targets for novel small-molecule...
10 KB (1,118 words) - 06:38, 27 April 2022
Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
35 KB (3,831 words) - 18:08, 20 August 2024
regulation of protein kinase family known as Aurora kinase. Aurora kinase has two forms which are designated Aurora kinase A and Aurora kinase B. These proteins...
5 KB (539 words) - 13:02, 18 August 2023
BI 811283 is a small molecule inhibitor of the Aurora B kinase protein being developed by Boehringer Ingelheim for use as an anti-cancer agent. BI 811283...
11 KB (1,107 words) - 19:33, 29 December 2023
The IκB kinase (IkappaB kinase or IKK) is an enzyme complex that is involved in propagating the cellular response to inflammation, specifically the regulation...
14 KB (1,447 words) - 09:31, 22 December 2023
which is slowly degraded by the internalising cell. MKLP1 TEX14 CEP55 Aurora Kinase B Paweletz N (January 2001). "Walther Flemming: pioneer of mitosis research"...
4 KB (446 words) - 06:52, 24 November 2022