protein-interacting protein 3 is a protein found in humans that is encoded by the BNIP3 gene. BNIP3 is a member of the apoptotic Bcl-2 protein family. It can induce cell...

degeneration. It is mediated by Atg32 (in yeast) and NIX and its regulator BNIP3 in mammals. Mitophagy is regulated by PINK1 and parkin proteins. In addition...

interact with: BAK1, BCAP31, BCL2-like 1, BCL2L11, BECN1, BID, BMF, BNIP2, BNIP3, BNIPL, BAD BAX, BIK, C-Raf, CAPN2, CASP8, Cdk1, HRK, IRS1, Myc, NR4A1,...

buildup of damaged mitochondria is sufficient levels of the protein BNIP3. Deficiency of BNIP3 leads to muscle inflammation and atrophy. Furthermore, not every...

this gene is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression...

HGNC:30988 Q6ZN30 1603 BNIP1 HGNC:1082 Q12981 1604 BNIP2 HGNC:1083 Q12982 1605 BNIP3 HGNC:1084 Q12983 1606 BNIP3L HGNC:1085 O60238 1607 BNIP5 HGNC:33769 P0C671...

lymphocytes by the process of mitophagy with the help of its regulator BNIP3. Using a gene knockout technique in mice, scientists have been able to attribute...

cells. The BNIP3 pathway involves mitochondrial release and nuclear translocation of the endonuclease G. It is not clear, however, that how BNIP3 interacts...

degeneration. It is mediated by Atg32 (in yeast) and NIX and its regulator BNIP3 in mammals. Mitophagy is regulated by PINK1 and parkin proteins. The occurrence...

factors, such as IAPs and Bcl-2 proteins or prosurvival factors like cFLIP, BNIP3, FADD, Akt, and NF-κB. Many pathways and signals lead to apoptosis, but...