Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those...
44 KB (3,705 words) - 04:59, 15 August 2024
Ticagrelor (section With clopidogrel)
whether clopidogrel is significantly influenced by such variants). Ticagrelor was found to result in a lower risk of stroke at 90 days than clopidogrel, which...
33 KB (3,121 words) - 08:30, 1 July 2024
PCI. Prasugrel is associated with a higher bleeding risk compared to clopidogrel but has demonstrated superiority in reducing the composite endpoint of...
20 KB (1,953 words) - 07:43, 27 May 2024
clopidogrel to prevent these events. This interaction is possible because omeprazole is an inhibitor of the enzymes CYP2C19 and CYP3A4. Clopidogrel is...
42 KB (3,798 words) - 21:42, 30 August 2024
ticlopidine but due to adverse effects it is not much used today. Ticlopidine, clopidogrel and prasugrel (Efient) are all thienopyridines that cause irreversible...
46 KB (5,282 words) - 08:16, 30 March 2024
drugs in current clinical use, most notably the antiplatelet treatment clopidogrel (Plavix), drugs that treat pain associated with ulcers, such as omeprazole...
39 KB (3,879 words) - 02:14, 11 August 2024
therapy. Often a combination of aspirin plus an ADP/P2Y inhibitor (such as clopidogrel, prasugrel, ticagrelor, or another) is used to obtain greater effectiveness...
18 KB (1,752 words) - 10:58, 11 August 2024
extended-release dipyridamole, or clopidogrel alone. Clopidogrel and aspirin have similar efficacies and side effect profiles. Clopidogrel is more expensive and has...
45 KB (5,116 words) - 15:37, 6 August 2024
increase if they are used concomitantly with esomeprazole. Conversely, clopidogrel (Plavix) is an inactive prodrug that partially depends on CYP2C19 for...
31 KB (2,741 words) - 18:31, 9 August 2024
desirable. With the advent of newer and safer antiplatelet drugs such as clopidogrel and ticagrelor, its use remained limited. It was patented in 1973 and...
18 KB (1,724 words) - 18:25, 20 June 2024