INK4 is a family of cyclin-dependent kinase inhibitors (CKIs). The members of this family (p16INK4a, p15INK4b, p18INK4c, p19INK4d) are inhibitors of CDK4...
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two primary CKI families exist: the INK4 family (p16, p15, p18, p19) and the CIP/KIP family (p21, p27, p57). The INK4 family proteins specifically bind...
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many tissues and cell types. The gene codes for two proteins, including the INK4 family member p16 (or p16INK4a) and p14arf. Both act as tumor suppressors...
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In 2009, Sharpless and his team were the first to discover altered human INK4/ARF expression as the mechanism for the 9p21.3 genetic risk allele of atherosclerosis...
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isoform '4' encodes p14(ARF), a protein that is structurally unrelated to p16(INK4) but acts in cell cycle G1 control by stabilizing the tumor suppressor protein...
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which the arteries become hard. It has been proposed that cANRIL can modify INK4/ARF expression, which, in turn, increases risk for atherosclerosis. Further...
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protein/Kinase inhibitory protein) family is one of two families (CIP/KIP and INK4) of mammalian cyclin dependent kinase (CDK) inhibitors (CKIs) involved in...
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June 1994). "Blue Tiger". Variety. Retrieved 16 June 2020. "First Look, Oz ink4-pic pact". Variety. Retrieved October 19, 2024. Mes, Tom (2024) [first published...
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original on November 21, 2007. Retrieved August 29, 2011. "First Look, Oz ink4-pic pact". Variety. Retrieved October 19, 2024. Mes, Tom (2024) [first published...
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008. PMC 4536333. PMID 25565328. Xian, T.; Azpurua, J. (27 January 2015). "INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional...
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