U.S. Route 22 (US 22) is a major west–east route and one of the original United States Numbered Highways, founded in 1926. It runs from Cincinnati, Ohio...

U.S. Route 22 (US 22) is an east–west United States Numbered Highway that stretches from Cincinnati, Ohio, in the west, to Newark, New Jersey, in the east...

U.S. Route 22 (US 22) is a United States Numbered Highway stretching from Cincinnati, Ohio, in the west to Newark, New Jersey, in the east. In New Jersey...

U.S. Route 322 (US 322) is a 494-mile-long (795.0 km), east–west United States Highway, traversing Ohio, Pennsylvania, and New Jersey. The road is a spur...

least eight special routes of U.S. Route 22 (US 22) have existed and at least six have been deleted. U.S. Route 22 Business (US 22 Bus.) is a five-mile...

U.S. Route 66 or U.S. Highway 66 (US 66 or Route 66) was one of the original highways in the United States Numbered Highway System. It was established...

U.S. Route 522 (US 522) is a spur route of US 22 in the states of Virginia, West Virginia, Maryland, and Pennsylvania. The U.S. Highway travels in a north-south...

U.S. Route 422 (US 422) is a 271-mile-long (436 km) spur route of US 22 split into two segments in the U.S. states of Ohio and Pennsylvania. The western...

U.S. Route 222 (US 222) is a U.S. Highway that is a spur of US 22 in the states of Maryland and Pennsylvania. It runs for 95 miles (153 km) from US 1...

U.S. Route 46 (US 46) is an east–west U.S. Highway completely within the state of New Jersey, running for 75.34 mi (121.25 km), making it the shortest...