G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. Cyclin B1 is a regulatory protein involved in mitosis. The gene...
25 KB (3,276 words) - 07:43, 10 June 2024
G2 phase (section Cyclin B1 synthesis and degradation)
threshold level of active cyclin-B1/CDK1 complex, also known as cyclin-B1/Cdc2 or the maturation promoting factor (MPF). Active cyclin-B1/CDK1 triggers irreversible...
22 KB (2,818 words) - 07:39, 3 June 2024
Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK). Cyclins were originally...
19 KB (1,760 words) - 14:59, 1 October 2024
Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk...
11 KB (1,334 words) - 11:01, 13 August 2023
Ollendorff V, Donoghue DJ (March 2000). "Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction". The EMBO Journal. 19...
25 KB (2,896 words) - 12:38, 29 August 2024
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,829 words) - 14:24, 17 June 2024
phenomenon is caused by improper degradation of cyclin B1 and can result in chromosome missegregation events. Cyclin B1 is a major regulator of the cell cycle...
30 KB (3,020 words) - 21:28, 3 June 2024
Lindqvist A, van Zon W, Karlsson Rosenthal C, Wolthuis RM (May 2007). "Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic...
41 KB (4,735 words) - 04:03, 18 November 2024
G0 phase (section Cyclin C/Cdk3 and Rb)
involves downregulation of cell cycle progression genes, such as cyclin A2, cyclin B1, cyclin E2, and survivin, and upregulation of genes involved in the regulation...
30 KB (3,755 words) - 01:51, 4 April 2024
promoting factor (MPF). Recent studies have shown that the cyclin A2-CDK1 complex triggers cyclin B1-CDK1 activation which results in chromatin condensation...
21 KB (2,580 words) - 03:53, 26 August 2024