Mouse models have frequently been used to study Down syndrome due to the close similarity in the genomes of mice and humans, and the prevalence of mice...
10 KB (1,313 words) - 14:17, 8 March 2024
mouse model systems include mouse models of colorectal and intestinal cancer, mouse models of Down syndrome and mouse models of breast cancer metastasis...
16 KB (1,769 words) - 01:18, 15 October 2024
Down syndrome (United States) or Down's syndrome (United Kingdom and other English-speaking nations), also known as trisomy 21, is a genetic disorder caused...
148 KB (14,803 words) - 07:34, 11 October 2024
eyes with down-slanting palpebral fissures, receding mandible and intellectual disability. A mouse model has been developed. This mouse model is characterized...
6 KB (468 words) - 16:55, 8 June 2024
Filippis B, Laviola G (2008). "Mouse models of Rett syndrome: From behavioural phenotyping to preclinical evaluation of new therapeutic approaches". Behavioural...
57 KB (6,112 words) - 02:38, 27 October 2024
Charles Epstein (geneticist) (category Members of the National Academy of Medicine)
chairman of the medical genetics division in the pediatrics department of UC San Francisco. He did research on making a mouse model for Down syndrome. Epstein...
7 KB (599 words) - 15:25, 24 July 2024
Tsuneko Okazaki (category Recipients of the Order of Culture)
2014). "A novel mouse model for Down syndrome that harbor a single copy of human artificial chromosome (HAC) carrying a limited number of genes from human...
12 KB (1,263 words) - 08:25, 19 September 2024
seen within dogs and mouse models, the genetic mutation has not been seen to manifest in humans. Symptoms due to Sanfilippo Syndrome arise because the body...
44 KB (5,110 words) - 20:17, 5 November 2024
DSCAM (section Regulation of synaptogenesis)
abbreviations for Down syndrome cell adhesion molecule. In humans, DSCAM refers to a gene that encodes one of several protein isoforms. Down syndrome (DS), caused...
32 KB (3,755 words) - 01:14, 13 August 2024
biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome". The Journal of Lipid Research. 52 (6): 1222–33. doi:10.1194/jlr...
56 KB (6,560 words) - 14:53, 22 October 2024