NEDD8 is a protein that in humans is encoded by the NEDD8 gene. (in Saccharomyces cerevisiae this protein is known as Rub1) This ubiquitin-like (UBL)...

Neddylation (also NEDDylation) is the process by which the ubiquitin-like protein NEDD8 is conjugated to its target proteins. This process is analogous to ubiquitination...

(MLN4924) is a selective NEDD8 inhibitor. It is being investigated as a cancer treatment, e.g. for mantle cell lymphoma (MCL). NEDD8-activating enzyme (NAE)...

in metazoans. The only identified Nedd8 substrates are cullins. Neddylation results in covalent conjugation of a Nedd8 moiety onto a conserved cullin lysine...

NEDD8-activating enzyme E1 regulatory subunit is a protein that in humans is encoded by the NAE1 gene. The protein encoded by this gene binds to the beta-amyloid...

preparation Massage, the rubbing or kneading of the body's soft tissues NEDD8, a protein in Saccharomyces cerevisiae known as Rub1 Rubredoxin A (RubA)...

Sentrin-specific protease 8 is an enzyme that in humans is encoded by the SENP8 gene. NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the...

is encoded by the UBA1 gene. UBA1 participates in ubiquitination and the NEDD8 pathway for protein folding and degradation, among many other biological...

enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like...

neuronal-precursor-cell-expressed developmentally downregulated protein-8 (NEDD8, also called Rub1 in S. cerevisiae), human leukocyte antigen F-associated...