Imipenem/cilastatin, sold under the brand name Primaxin among others, is an antibiotic useful for the treatment of a number of bacterial infections. It...

Cilastatin inhibits the human enzyme dehydropeptidase. Dehydropeptidase is an enzyme found in the kidney and is responsible for degrading the antibiotic...

Imipenem/cilastatin/relebactam, sold under the brand name Recarbrio, is a fixed-dose combination medication used as an antibiotic. In 2019, it was approved...

dehydropeptidase 1 when administered alone, and is almost always coadministered with cilastatin to prevent this inactivation. Common adverse drug reactions are nausea...

Carbapenems: (meropenem, imipenem/cilastatin, doripenem - NOT ertapenem) Meropenem/vaborbactam Imipenem/cilastatin/relebactam Others: Fluoroquinolones:...

1984 – cefotetan 1984 – temocillin 1985 – cefpiramide 1985 – imipenem/cilastatin, the first carbapenem 1985 – ofloxacin 1986 – mupirocin 1986 – aztreonam...

to receive cefiderocol, or another antibacterial drug called imipenem/cilastatin. Both treatments were given intravenously for 7–14 days and neither the...

intermediate, and thus is co-formulated with the dehydropeptidase inhibitor cilastatin. Imipenem is available in both intravenous and intramuscular formulations...

combination with meropenem or imipenem/cilastatin. Terizidone is an alternative Prothionamide is an alternative Imipenem/cilastatin is an alternative For treatment...

to the duration of treatment according to infected sites. The imipenem/cilastatin, clindamycin, or combinations containing an inhibitor of beta-lactamases...