rickets. Fibroblast growth factor 23 (FGF23) is a protein which in humans is encoded by the FGF23 gene. FGF23 is a member of the fibroblast growth factor...

mutations lead to an elevated circulating (systemic) level of the hormone FGF23 which results in renal phosphate wasting, and local elevations of the...

caused by overproduction of a hormone called FGF23 (fibroblast growth factor 23) in bone cells. FGF23 is responsible for blocking phosphate re-absorption...

tumor-induced osteomalacia, a paraneoplastic syndrome, by the secretion of FGF23, which has phosphaturic activity (by inhibition of renal tubular reabsorption...

23 (FGF23), a hormone that regulates phosphate homeostasis by decreasing the reabsorption of phosphate in the kidneys. Elevated levels of FGF23 in phosphate...

subfamilies of klotho are α-klotho, β-klotho, and γ-klotho. α-klotho activates FGF23, and β-klotho activates FGF19 and FGF21. When the subfamily is not specified...

identified based on its homology to Xenopus FGF-20 (XFGF-20). FGF15 through FGF23 were described later and functions are still being characterized. FGF15...

of serum phosphate and by an increase in the production of the hormone FGF23 by osteocyte cells in bone. Calcitriol is also produced outside the kidney...

kidneys where it is principally regulated by parathyroid hormone, but also by FGF23 and calcitriol itself. CYP27B1 is also expressed in a number of other tissues...

hypocalcemia). Calcitriol Increase in serum phosphate. Fibroblast growth factor-23 (FGF23) is produced in osteoblasts (from bone) in response to increases in serum...