alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is encoded by the HNF4A gene....

specific mutation (R76W) of HNF4A, a gene encoding a transcription factor, causes Fanconi syndrome in human. In the kidney, HNF4A is expressed in the proximal...

consistent decrease in gliclazide clearance in randomly selected HNF1A-MODY and HNF4A-MODY patients. Its classification has been ambiguous, as literature uses...

decrease in the clearance of sulfonylureas in randomly selected HNF1A-MODY and HNF4A-MODY patients. Chronic hyperglycemia due to any cause can eventually cause...

hepatocyte nuclear factor 4 alpha (HNF4A) binding to a DR1 like cis element which then stimulate production. Competing with HNF4A at a third site on the promoter...

subsection) Glycogenosis-like phenotype of congenital hyperinsulinism due to HNF4A mutation or MODY1 (maturity-onset diabetes of the young, type 1). This phenotype...

are two paralogs of HNF4, HNF4α and HNF4γ, encoded by two separate genes HNF4A and HNF4G respectively. HNF4 was originally classified as an orphan receptor...

MODY 1 or HNF4A-MODY is a form of maturity onset diabetes of the young. MODY 1 is due to a loss-of-function mutation in the HNF4A (MODY1) gene on chromosome...

Homeodomain Known motif – High-throughput in vitro [368] GTTAATNATTAAY HNF4A ENSG00000101076 Nuclear receptor Known motif – High-throughput in vitro...

A Hepatocyte nuclear factor-4 NR2A1 HNF4α Hepatocyte nuclear factor-4-α HNF4A fatty acids NR2A2 HNF4γ Hepatocyte nuclear factor-4-γ HNF4G B Retinoid X...