nuclear localization sequences (NLS). Importin has two subunits, importin α and importin β. Members of the importin-β family can bind and transport cargo...

complexes. Importin beta is a variety of karyopherin that facilitates the transport of cargo proteins into the nucleus. First, it is binding importin alpha...

signals are recognized by importin α. Importin α contains a bipartite NLS itself, which is specifically recognized by importin β. The latter can be considered...

Importin alpha, or karyopherin alpha refers to a class of adaptor proteins that are involved in the import of proteins into the cell nucleus. They are...

Importin subunit alpha-1 is a protein that in humans is encoded by the KPNA2 gene. The import of proteins into the nucleus is a process that involves at...

Transportin-1 (or Importin-β 2) is a protein that in humans is encoded by the TNPO1 gene. This protein is a karyopherin which interacts with nuclear localization...

Importin subunit alpha-5 is a protein that in humans is encoded by the KPNA1 gene. Importin subunit alpha-5 has been shown to interact with KPNB1 and...

Importin subunit alpha-7 is a protein that in humans is encoded by the KPNA6 gene. Nucleocytoplasmic transport, a signal- and energy-dependent process...

material with an NLS will be taken up by importins to the nucleus.[citation needed] Importation begins with Importin-α binding to the NLS sequence of cargo...

called importins. Once the STAT dimer (bound to importins) enters the nucleus, a protein called Ran (associated with GTP) binds to the importins, releasing...