Homeobox protein OTX2 is a protein that in humans is encoded by the OTX2 gene. This gene encodes a member of the bicoid sub-family of homeodomain-containing...

profiles of the retinas of wild-type and Otx2 knockout mice. A RT-PCR analysis was used to confirm that Otx2 regulates the expression of pikachurin, it...

HCCS HMGB3 HMX1 IGBP1 KAT6B KMT2D LRP2 MAB21L2 MAF MFRP NAA10 NDUFB11 NHS OTX2 PAX2 PAX6 PDE6D PIGL POLR1C POLR1D PORCN PQBP1 PRSS56 PTCH1 RAB3GAP1 RAB3GAP2...

called Joubert Syndrome, a disorder that affects the cerebellum. Otx1 and Otx2 are genes that play important parts in the development of the brain, and...

genomes to the human genome at the conserved OTX2 gene. Top: Gene annotations of exons and introns of the OTX2 gene. For each genome, sequence similarity...

show that Fez is required for prethalamus formation. Posteriorly, Otx1 and Otx2 abut the expression domain of Fez and are required for proper development...

and location of the MHB is mediated by the transcription factors Otx2 and Gbx2. Otx2 is expressed in the anterior neural tube and cells in the posterior...

differentiation are induced by several transcription factors, including RORbeta, OTX2, NRL, CRX, NR2E3 and TRbeta2. The S cone fate represents the default photoreceptor...

heterozygous mutations are mildly affected. In addition to HESX1, mutations in OTX2, SOX2 and PAX6 have been implicated in SOD. SOX2 mutations in SOD patients...

performed in zebrafish have revealed the significance of OTX2 and IRX1 in ZLI positioning. OTX2 expression characterizes the developing optic tectum, which...