Taxanes are a class of diterpenes. They were originally identified from plants of the genus Taxus (yews), and feature a taxadiene core. Paclitaxel (Taxol)...

(mBC) in patients who have been treated previously with trastuzumab and a taxane (paclitaxel or docetaxel), and who have already been treated for mBC or...

In enzymology, a taxane 13alpha-hydroxylase (EC 1.14.13.77) is an enzyme that catalyzes the chemical reaction taxa-4(20),11-dien-5alpha-ol + NADPH + H+...

In enzymology, a taxane 10beta-hydroxylase (EC 1.14.13.76) is an enzyme that catalyzes the chemical reaction taxa-4(20),11-dien-5alpha-yl acetate + NADPH...

agents include taxanes and epothilones, both of which prevent cancer cells from dividing by interfering with tubulin. While taxanes like Paclitaxel and...

liver problems. Use during pregnancy may harm the baby. Docetaxel is in the taxane family of medications. It works by disrupting the normal function of microtubules...

and include important compounds such as retinol, phytol or taxadiene. Taxanes are class of diterpenoids featuring a taxadiene core. They are produced...

Taxamairin A is a non-taxane isolate of Taxus yunnanensis. Li SH, Zhan HJ, Yao P, Niu XM, Xiang W, Sun HD (2002). "Non-taxane compounds from the bark...

paclitaxel or docetaxel. The core carbon skeleton of a normal natural product taxane (e.g., paclitaxel, docetaxel) has a 6-membered A ring, 8-membered B ring...

derivative of a natural taxoid. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.[citation needed] Cabazitaxel was developed...