Cohesin is a protein complex that mediates sister chromatid cohesion, homologous recombination, and DNA looping. Cohesin is formed of SMC3, SMC1, SCC1...
31 KB (3,806 words) - 16:36, 7 May 2024
across species and are highly enriched with CCCTC-binding factor (CTCF) and cohesin. In addition, some types of genes (such as transfer RNA genes and housekeeping...
29 KB (3,140 words) - 02:23, 5 May 2024
molecular biology, the cohesin domain is a protein domain. It interacts with a complementary domain, termed the dockerin domain. The cohesin-dockerin interaction...
2 KB (157 words) - 06:44, 29 October 2023
control. The cohesin complex is responsible for keeping together sister chromatids and provides binding sites for spindle attachment. Cohesin is loaded onto...
25 KB (2,857 words) - 18:11, 18 May 2024
proteins that function in the cohesin pathway. SMC1A, SMC3 and RAD21 proteins are structural components of the cohesin ring complex. NIPBL is involved...
26 KB (3,012 words) - 19:53, 23 August 2024
Spindle checkpoint (section Cohesin: SMC proteins)
the cohesin complex suggests that this complex connects directly both sister chromatids. In this proposed structure, the SMC components of cohesin play...
73 KB (9,145 words) - 07:11, 31 August 2024
humans. RAD21 protein is a structural component of the highly conserved cohesin complex consisting of RAD21, SMC1A, SMC3, and SCC3 [ STAG1 (SA1) and STAG2...
57 KB (5,500 words) - 03:35, 15 April 2024
down the center. Unlike in mitosis, only the cohesin from the chromosome arms is degraded while the cohesin surrounding the centromere remains protected...
64 KB (7,478 words) - 23:27, 22 August 2024
The destruction of securin unleashes separase which then breaks down cohesin, a protein responsible for holding sister chromatids together. At this...
6 KB (719 words) - 02:00, 2 May 2024
a cysteine protease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during...
10 KB (1,199 words) - 03:08, 12 April 2024