• Thumbnail for Major prion protein
    major prion protein (PrP) is encoded in the human body by the PRNP gene also known as CD230 (cluster of differentiation 230). Expression of the protein is...
    45 KB (5,140 words) - 04:58, 3 August 2024
  • Thumbnail for Prion
    A prion /ˈpriːɒn/ is a misfolded protein that can induce misfolding of normal variants of the same protein and trigger cellular death. Prions cause prion...
    100 KB (10,911 words) - 07:59, 17 August 2024
  • Thumbnail for Transmissible spongiform encephalopathy
    animal with no prion protein mutation. Inherited TSE occurs in animals carrying a rare mutant prion allele, which expresses prion proteins that contort...
    40 KB (4,423 words) - 07:59, 17 August 2024
  • Thumbnail for Creutzfeldt–Jakob disease
    abnormal folding of a protein known as a prion. Infectious prions are misfolded proteins that can cause normally folded proteins to also become misfolded...
    69 KB (7,481 words) - 12:29, 16 August 2024
  • Thumbnail for Kuru (disease)
    Kuru (disease) (category Prions)
    encephalopathy (TSE) caused by the transmission of abnormally folded proteins (prions), which leads to symptoms such as tremors and loss of coordination...
    33 KB (3,760 words) - 22:34, 15 August 2024
  • Thumbnail for Scrapie
    accumulation of prions in the central nervous system, and immunohistochemical staining and ELISA can also be used to demonstrate the protein. No treatment...
    43 KB (5,044 words) - 13:11, 14 May 2024
  • Thumbnail for Variant Creutzfeldt–Jakob disease
    following the onset of symptoms is 13 months. It is caused by prions, which are misfolded proteins. Spread is believed to be primarily due to eating bovine...
    45 KB (4,530 words) - 01:20, 6 August 2024
  • Thumbnail for Gerstmann–Sträussler–Scheinker syndrome
    encephalopathies (TSE) due to the causative role played by PRNP, the human prion protein. GSS was first reported by the Austrian physicians Josef Gerstmann,...
    14 KB (1,426 words) - 04:26, 21 June 2024
  • Thumbnail for Fatal insomnia
    rare hereditary prion disease that is associated with a mutation in PRNP. The gene, which provides instructions for making the prion protein PrPC, is located...
    26 KB (2,885 words) - 03:16, 16 July 2024
  • Thumbnail for Fungal prion
    A fungal prion is a prion that infects hosts which are fungi. Fungal prions are naturally occurring proteins that can switch between multiple, structurally...
    23 KB (2,738 words) - 14:54, 15 August 2024