Trametinib, sold under the brand name Mekinist among others, is an anticancer medication used for the treatment of melanoma and glioma. It is a MEK inhibitor...

rash, joint pain, fever and tiredness. When taken in combination with trametinib, the most common side effects include fever, tiredness, nausea, chills...

BRAF inhibitors, such as vemurafenib and dabrafenib and a MEK inhibitor trametinib are the most effective, approved treatments for BRAF positive melanoma...

BRAF inhibitors, such as vemurafenib and dabrafenib; and a MEK inhibitor trametinib. Important prognosis factors for nodular melanoma include: Thickness Ulceration...

of NSCLC) can be treated by dabrafenib combined with the MEK inhibitor trametinib; those with activated ROS1 (around 1% of NSCLC) can be inhibited by crizotinib...

evaluated as a combination treatment against solid tumors together with trametinib in a clinical trial sponsored by the National Cancer Institute. In this...

metastatic melanoma that harbors BRAF V600E mutation MEK inhibitors (trametinib, MEK162) are used in experiments, often in combination with BRAF inhibitors...

Rosuvastatin Crestor 1.37 in hemodialysis patients Lisinopril Prinivil and others 1.38 Ivacaftor Kalydeco 2.2–2.9 Trametinib Mekinist 6.0 at 2 mg once daily...

BRAF inhibitors, such as vemurafenib and dabrafenib; and a MEK inhibitor trametinib. When arising in the nailbed of a digit, the evidence suggests that digit-sparing...

Fecher, Leslie A.; et al. (2012). "Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial"....