Hepcidin is a protein that in humans is encoded by the HAMP gene. Hepcidin is a key regulator of the entry of iron into the circulation in mammals. During...

produce elevation of interleukin-6, which stimulates hepcidin production and release from the liver. Hepcidin production and release shuts down ferroportin,...

regulatory protein hepcidin are thought to play an integral role in the pathogenesis of hereditary hemochromatosis. Normally, hepcidin acts to reduce iron...

overweight Decreased levels of serum and urine hepcidin are early indicators of iron deficiency. Hepcidin concentrations are also connected to the complex...

hormone hepcidin may play a role in the regulation of hemoglobin production, and thus affect erythropoiesis. The liver produces hepcidin. Hepcidin controls...

the spleen and liver. Ferroportin is regulated by hepcidin, a hormone produced by the liver; hepcidin binds to Fpn and limits its iron-efflux activity...

to produce the iron metabolism regulator protein hepcidin, that reduces available iron. If hepcidin levels increase because of non-bacterial sources of...

TFR2. Hepcidin is the master regulator of iron metabolism and, therefore, most genetic forms of iron overload can be thought of as relative hepcidin deficiency...

Erythroferrone is produced by erythroblasts, inhibits the production of hepcidin in the liver, and so increases the amount of iron available for hemoglobin...

Hepcidin levels in the liver are dramatically depressed in these knockout animals. A soluble form of HJV may be a molecule that suppresses hepcidin expression...