Jagged1 (JAG1) is one of five cell surface proteins (ligands) that interact with four receptors in the mammalian Notch signaling pathway. The Notch signaling...
21 KB (2,693 words) - 07:17, 11 September 2024
in either JAG1 (Jagged1) or NOTCH2 (Notch homolog 2). In the majority of people with ALGS, the gene mutation occurs in the JAG1 gene. The JAG1 mutation...
20 KB (2,205 words) - 23:32, 19 September 2024
with CSF-1 50% FOXL2 point mutation (402 C to G) adult granulosa cell ~100% JAG1 amplification 2% JAG2 amplification 3% KRAS amplification mucinous and low-grade...
198 KB (21,235 words) - 01:51, 17 October 2024
include: JAG1 codes for ligands within the Notch family of proteins and is highly expressed in the developing heart. Mutations of the JAG1 gene can lead...
78 KB (8,318 words) - 00:47, 2 October 2024
recessive Adrenoleukodystrophy ABCD1 (X) recessive 1:17,000 Alagille syndrome JAG1, NOTCH2 dominant 1:30,000-50,000 ADULT syndrome TP63 dominant Aicardi–Goutières...
42 KB (983 words) - 18:14, 6 October 2024
clash for classmates and friends, writing his own lyrics and formed the JAG1 (Jah A Guide)(JOP) crew with friends. After being expelled, he relocated...
5 KB (529 words) - 20:16, 19 June 2024
CD339 JAG1 (Jagged 1). One of five cell surface proteins (ligands) that interact with 4 receptors in the mammalian Notch signaling pathway. The JAG1 gene...
96 KB (467 words) - 19:33, 6 August 2024
immune cells) B7/H1 – decreasing proliferation of effector T-cells Jagged1 (JAG1) – induction of Foxp3 transcription factor expression in naive T lymphocytes...
26 KB (3,061 words) - 14:02, 25 September 2024
genetic (Autosomal dominant inheritance: loss of function mutations in either JAG1 or NOTCH2) Congenital heart problems e.g. pulmonary artery stenosis (common)...
6 KB (113 words) - 09:28, 23 January 2021
Delta-like 4 (DLL4) and Jagged1 (Jag1) as a means of stabilizing the complexes for co-crystallization. Notch1-DLL4 and Notch1-Jag1 structures were determined...
23 KB (2,278 words) - 21:07, 11 September 2024