Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant. Opioids work in the brain to produce a variety...
222 KB (19,664 words) - 05:47, 7 October 2024
The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either...
79 KB (8,426 words) - 03:16, 6 September 2024
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
40 KB (4,427 words) - 12:37, 12 January 2024
An opioid antagonist, or opioid receptor antagonist, is a receptor antagonist that acts on one or more of the opioid receptors. Naloxone and naltrexone...
11 KB (1,340 words) - 14:34, 24 July 2024
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins...
49 KB (4,885 words) - 11:31, 6 October 2024
There is an ongoing opioid epidemic (also known as the opioid crisis) in the United States, originating out of both medical prescriptions and illegal...
250 KB (25,797 words) - 02:12, 2 October 2024
Opioid use disorder (OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration...
125 KB (13,392 words) - 03:24, 28 September 2024
Naloxone (category Kappa-opioid receptor antagonists)
an opioid antagonist: a medication used to reverse or reduce the effects of opioids. For example, it is used to restore breathing after an opioid overdose...
81 KB (7,399 words) - 06:10, 6 October 2024
An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. This preventable...
52 KB (5,487 words) - 07:02, 14 September 2024
Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden withdrawal or reduction of opioids where previous usage has been heavy and...
14 KB (1,582 words) - 02:57, 21 August 2024