PyBOP (benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate) is a reagent used to prepare amides from carboxylic acids and amines in the...
5 KB (265 words) - 16:19, 3 August 2024
differential scanning calorimetry (DSC) shows PyAOP is potentially explosive. HOAt reagent HOBt reagent BOP reagent PyBOP Mansour, Tarek S.; Bardhan, Sujata; Wan...
5 KB (350 words) - 16:17, 3 August 2024
Peptide synthesis (redirect from BOP-Cl)
N-form is generally more stable. Phosphonium reagents include BOP (HOBt), PyBOP (HOBt) and PyAOP (HOAt). Although these reagents can lead to the same activated...
54 KB (6,100 words) - 16:21, 3 August 2024
is produced as a stoichiometric by-product. PyBOP, a related phosphonium reagent for amide bond formation PyAOP, a related phosphonium reagent for amide...
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RC(O)NR'2 + RCO2H Peptide synthesis use coupling agents such as HATU, HOBt, or PyBOP. The hydrolysis of nitriles is conducted on an industrial scale to produce...
21 KB (2,073 words) - 22:46, 27 July 2024
calorimetry (DSC) shows HBTU is potentially explosive. EDC HATU BOP reagent PyBOP PyAOP reagent CID 2733084 from PubChem "2-(1h-Benzotriazole-1-yl)-1...
8 KB (639 words) - 12:03, 1 August 2024
tautomerizable heterocycle is activated with a phosphonium salt (PyBroP, PyBOP, BroP, or BOP), and subsequent functionalization with either a nucleophile...
3 KB (429 words) - 00:36, 26 August 2022
during SPPS, though the approach was regarded as 'costly and tedious'. BOP PyBOP Li, Haitao; Jiang, Xiaohui; Ye, Yun-hua; Fan, Chongxu; Romoff, Todd; Goodman...
3 KB (179 words) - 01:47, 26 August 2023
amide Retosiban 8 by activating the acid with the peptide coupling reagent PyBOP (benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate) followed...
10 KB (1,099 words) - 16:40, 19 December 2023
Biochemistry. 36 (7): 1836–45. doi:10.1021/bi962476u. PMID 9048568. Kwok PY, Muellner FW, Fried J (June 1987). "Enzymatic conversions of 10,10-difluoroarachidonic...
30 KB (3,417 words) - 14:36, 15 May 2024