receptor 1 or S1PR1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled...
21 KB (2,449 words) - 19:21, 2 June 2024
complex with S1PR1 (not S1PR3 or S1PR5). This association is dependent on the interaction between the CD69 transmembrane domain and helix-4 of S1PR1. Following...
18 KB (2,275 words) - 00:54, 26 March 2024
Sphingosine-1-phosphate (S1P). They are divided into five subtypes: S1PR1, S1PR2, S1PR3, S1PR4 and S1PR5. In 1990, S1PR1 was the first member of the S1P receptor family to...
12 KB (1,266 words) - 08:05, 18 August 2023
lie in its activity at one of the five sphingosine-1-phosphate receptors, S1PR1. Phospho-fingolimod causes the internalization of S1P receptors, which sequesters...
27 KB (2,574 words) - 15:29, 18 October 2024
identification of dermopterans as the closest primate relatives. Source: CNR2 S1PR1 LPAR1 S1PR3 S1PR5 S1PR2 GPR6 GPR12 S1PR4 LPAR3 LPAR2 GPR3 MC3R MC5R MC2R...
42 KB (4,331 words) - 16:48, 2 November 2024
1-phosphate receptor InterPro: IPR004061 Sphingosine 1-phosphate receptor 1 (S1PR1) Sphingosine 1-phosphate receptor 2 (S1PR2) Sphingosine 1-phosphate receptor...
25 KB (2,172 words) - 01:01, 29 November 2023
CD361 Also known as EVI2B. CD362 Also known as SDC2, Syndecan-2. CD363 S1PR1 (Sphingosine-1-phosphate receptor 1) or EDG1. It is a G-protein-coupled...
96 KB (492 words) - 17:19, 10 November 2024
discovered to be an extracellular ligand for G protein-coupled receptor S1PR1 in 1998. It is now known that sphingosine-1-phosphate receptors (S1P receptors)...
25 KB (2,659 words) - 02:02, 10 July 2024
purpurea AM-630 BML-190 JTE-907 SR-144,528 APD371 Source: CNR1 GPR12 GPR6 S1PR1 S1PR4 S1PR3 S1PR5 S1PR2 LPAR1 GPR3 LPAR3 LPAR2 MC4R MC5R GPR119 MC1R MC3R...
36 KB (3,887 words) - 16:09, 22 September 2024
inhibits binding to the receptor altogether. Source: MC4R MC3R MC5R MC1R GPR12 S1PR1 S1PR2 LPAR1 CNR1 S1PR3 GPR6 GPR3 S1PR5 LPAR3 S1PR4 CNR2 GPR119 LPAR2 melanocortin...
20 KB (2,316 words) - 22:00, 18 March 2024