Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...
44 KB (4,830 words) - 18:56, 11 August 2024
Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions...
50 KB (5,683 words) - 05:16, 29 June 2024
Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly...
31 KB (3,370 words) - 18:46, 11 August 2024
Amylin (redirect from Pro-islet amyloid polypeptide)
89-residue coding sequence. Proislet amyloid polypeptide (proIAPP, proamylin, proislet protein) is produced in the pancreatic beta cells (β-cells) as a 67 amino...
33 KB (4,044 words) - 04:41, 6 May 2024
Biochemistry of Alzheimer's disease (redirect from Amyloid hypothesis)
disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. Amyloid beta is a short peptide that is an abnormal proteolytic...
65 KB (7,761 words) - 08:45, 1 July 2024
Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the central...
18 KB (1,768 words) - 23:46, 18 June 2024
Swedish variant of Alzheimer's amyloid precursor protein. BACE2 is a close homolog of BACE1. Cerebral deposition of amyloid beta peptide is an early and critical...
12 KB (1,586 words) - 18:28, 8 November 2023
Lecanemab (category Anti-amyloid monoclonal antibodies)
medication used for the treatment of Alzheimer's disease. Lecanemab is an amyloid beta-directed antibody. It is given via intravenous infusion. The most common...
25 KB (2,098 words) - 00:31, 13 August 2024
peptides, 39–43 amino acids in length, called amyloid beta. Amyloid beta is a fragment from the larger amyloid-beta precursor protein (APP) a transmembrane...
182 KB (19,287 words) - 09:30, 18 August 2024
Presenilin-1 (section Beta-amyloid production)
important role in generation of amyloid beta (Aβ) from amyloid-beta precursor protein (APP). Accumulation of amyloid beta is associated with the onset of...
25 KB (3,113 words) - 11:23, 31 December 2023