• Thumbnail for Prokineticin receptor 2
    receptor 2 (PKR2), is a dimeric G protein-coupled receptor encoded by the PROKR2 gene in humans. Prokineticins are secreted proteins that can promote angiogenesis...
    7 KB (808 words) - 02:51, 10 March 2024
  • condition. It is associated with mutations in KAL1, FGFR1/FGF8, FGF17, IL17RD, PROKR2, NELF, CHD7(which positively regulates GnRH secretion), HS6ST1, FLRT3, SPRY4...
    6 KB (518 words) - 14:47, 15 September 2023
  • development of the hypothalamus and olfactory bulbs, including KAL1, FGFR1, FGF8, PROKR2, and PROK2. These mutations disrupt the migration of GnRH-producing neurons...
    46 KB (5,123 words) - 00:56, 21 September 2024
  • P58294 12863 PROK2 HGNC:18455 Q9HC23 12864 PROKR1 HGNC:4524 Q8TCW9 12865 PROKR2 HGNC:15836 Q8NFJ6 12866 PROM1 HGNC:9454 O43490 12867 PROM2 HGNC:20685 Q8N271...
    282 KB (17 words) - 18:42, 6 October 2024
  • Thumbnail for Female infertility
    Prokineticin Normosmic hypogonadotrophic hypogonadism and Kallmann syndrome (KAL4) PROKR2 Prokineticin receptor 2 Kallmann syndrome (KAL3) RSPO1 R-spondin family...
    63 KB (7,112 words) - 11:14, 23 July 2024
  • Thumbnail for Rhodopsin-like receptors
    InterPro: IPR001402 Prokineticin receptor 1 (PROKR1, GPR73) Prokineticin receptor 2 (PROKR2, PKR2) GPR19 (GPR19, GPRJ) GPR50 (GPR50, ML1X) GPR75 (GPR75) GPR83 (GPR83...
    25 KB (2,172 words) - 01:01, 29 November 2023
  • specification, fate, migration, and survival of GnRH-secreting neurons, PROKR2 and KAL1, which enable the migration of GnRH-secreting neurons, and GNRHR...
    81 KB (9,330 words) - 17:47, 9 June 2024
  • prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2). These receptors mediate gastrointestinal smooth muscle contraction and...
    2 KB (145 words) - 02:51, 10 March 2024
  • Thumbnail for Genetics of GnRH deficiency conditions
    dominant 3-6, <2 610628 KAL4 PROK2 3p13 Autosomal recessive 3-6, 5 244200 KAL3 PROKR2 20p12.3 Combined pituitary hormone deficiency. Morning Glory syndrome Autosomal...
    12 KB (612 words) - 10:54, 4 January 2024
  • 175050; MADH4 Kallmann syndrome 2; 147950; FGFR1 Kallmann syndrome 3; 244200; PROKR2 Kallmann syndrome 4; 610628; PROK2 Kallmann syndrome 5; 612370; CHD7 Kallmann...
    234 KB (18,877 words) - 15:43, 9 May 2024