• Thumbnail for CD154
    CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules...
    15 KB (1,744 words) - 05:04, 10 August 2024
  • Thumbnail for CD40 (protein)
    antigen-presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces...
    22 KB (2,805 words) - 03:33, 23 July 2024
  • Thumbnail for Seth Lederman
    As assistant professor at Columbia, Lederman discovered the CD40-Ligand (CD154) and elucidated the molecular basis of T cell helper function. He also collaborated...
    14 KB (1,317 words) - 22:18, 12 February 2024
  • Thumbnail for Tumor necrosis factor
    BAFF (CD257, TNFSF13B) CAML CD70 (CD27L, TNFSF7) CD153 (CD30L, TNFSF8) CD154 (CD40L, TNFSF5) Ectodysplasin (A, A2) FasL (CD95L, TNFSF6) GITRL (TNFSF18)...
    51 KB (6,200 words) - 17:14, 5 August 2024
  • Thumbnail for T helper cell
    immune response.[citation needed] In 1991, three groups reported discovering CD154, which is the molecular basis of T cell helper function. Seth Lederman at...
    54 KB (6,597 words) - 14:51, 21 July 2024
  • Thumbnail for Cytotoxic T cell
    antigen-presenting cells by the CD4+ T helper cells proceeds by signaling between CD154/CD40L on the T helper cell and the CD40 receptor on the antigen-presenting...
    31 KB (3,843 words) - 10:18, 12 August 2024
  • Thumbnail for Immune system
    molecules expressed on the T cell's surface, such as CD40 ligand (also called CD154), which provide extra stimulatory signals typically required to activate...
    119 KB (13,494 words) - 08:00, 4 August 2024
  • CD141 CD142 CD143 CD144 CD146 CD147 CD148 CD150 151–200 CD151 CD152 CD153 CD154 CD155 CD156 a b c CD157 CD158 (a d e i k) CD159 a c CD160 CD161 CD162 CD163...
    11 KB (1,311 words) - 20:50, 18 October 2022
  • Thumbnail for Programmed cell death protein 1
    CD141 CD142 CD143 CD144 CD146 CD147 CD148 CD150 151–200 CD151 CD152 CD153 CD154 CD155 CD156 a b c CD157 CD158 (a d e i k) CD159 a c CD160 CD161 CD162 CD163...
    39 KB (5,010 words) - 21:07, 27 June 2024
  • Thumbnail for Sjögren syndrome
    Szodoray P, Loro LL, Johannessen AC, Jonsson R (December 2002). "CD40, CD154, Bax and Bcl-2 expression in Sjögren's syndrome salivary glands: a putative...
    85 KB (9,050 words) - 01:29, 26 June 2024