Pirfenidone, sold under the brand name Pirespa among others, is a medication used for the treatment of idiopathic pulmonary fibrosis. It works by reducing...

pulmonary rehabilitation and supplemental oxygen. Certain medications like pirfenidone (Esbriet) or nintedanib (Ofev) may slow the progression of the disease...

in mild idiopathic fibrosis are pirfenidone, which reduced reductions in the 1-year rate of decline in FVC. Pirfenidone also reduced the decline in distances...

fibrosis) and 6.7 years in those with other types of ILD. The antifibrotics pirfenidone and nintedanib have been shown to slow the decline in lung function (as...

Y, Wang Y, Wang C, Tian M, Gu X, Lv W (2021). "Inhibitory effect of pirfenidone on pulmonary fibrosis in patients with acute paraquat poisoning". Am...

Sandoval-Rodriguez A, Monroy-Ramirez HC, Meza-Rios A, et al. (March 2020). "Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK"...

idiopathic pulmonary fibrosis, certain medications like nintedanib and pirfenidone can help slow the progression. Lastly, lung transplants may help. Regardless...

analgesia. Erivedge (vismodegib), for basal-cell carcinoma. Esbriet (pirfenidone), for idiopathic pulmonary fibrosis. Fansidar (sulfadoxine/pyrimethamine)...

breakthrough therapy designation to receive FDA approval. 2014: Esbriet (pirfenidone): An anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis...

Montes de Oca-Luna R, et al. (April 2020). "Efficacy and Safety of Pirfenidone in Patients with Second-Degree Burns: A Proof-of-Concept Randomized Controlled...