Cetuximab (section KRAS Testing)
panitumumab. Accordingly, genetic testing to confirm the absence of KRAS mutations (and so the presence of the KRAS wild-type gene), is now clinically...
26 KB (2,420 words) - 02:40, 26 September 2024
Molecular diagnostics (category Medical tests)
Boscaro V, Medico E, Weiser M, Siena S, Di Nicolantonio F, Solit D, Bardelli A (June 2012). "Emergence of KRAS mutations and acquired resistance to anti-EGFR...
39 KB (4,605 words) - 03:49, 13 July 2024
negative for CK20, p16 and p53. On genetic testing, KRAS and p53 are typically altered. Mahendraraj K, Di Como JA, Chamberlain RS (October 2014). "Adenosquamous...
4 KB (290 words) - 21:03, 28 August 2023
and then to a tumor. More than 90% of cases at all grades carry a faulty KRAS gene, while in grades 2 and 3, damage to three further genes – CDKN2A (p16)...
122 KB (12,761 words) - 07:50, 12 September 2024
Washington, D.C., USA, April. 2010 Di Nicolantonio F, Arena S, Tabernero J, et al. (August 2010). "Deregulation of the PI3K and KRAS signaling pathways in human...
21 KB (2,046 words) - 17:12, 15 December 2023
Multiple myeloma (section Blood tests)
pathways. Associated genetic mutations include ATM, BRAF, CCND1, DIS3, FAM46C, KRAS, NRAS and TP53. The genetic and epigenetic changes occur progressively. The...
131 KB (13,506 words) - 14:36, 4 September 2024
Colorectal cancer (redirect from Multitarget stool DNA screening test)
overexpressed in colorectal cancer. For example, genes encoding the proteins KRAS, RAF, and PI3K, which normally stimulate the cell to divide in response to...
145 KB (15,781 words) - 14:59, 27 September 2024
cases), EGFR (27%), KRAS (32%), KEAP1, STK11 and NF1. EGFR and KRAS mutations tend to appear in a mutually exclusive fashion. KRAS mutations are associated...
42 KB (4,603 words) - 02:26, 2 September 2024
Zulueta-Coarasa T, Slattum GM, Redd NM, Jin MF, Redd MJ, et al. (December 2021). "KRas-transformed epithelia cells invade and partially dedifferentiate by basal...
32 KB (2,883 words) - 03:28, 16 September 2024
August 2006. "Customs Services Department – Frequently Asked Questions". KRA. Archived from the original on 25 December 2018. Retrieved 12 December 2010...
135 KB (9,190 words) - 23:47, 17 September 2024