Cohesin is a protein complex that mediates sister chromatid cohesion, homologous recombination, and DNA looping. Cohesin is formed of SMC3, SMC1, SCC1...
31 KB (3,806 words) - 16:36, 7 May 2024
molecular biology, the cohesin domain is a protein domain. It interacts with a complementary domain, termed the dockerin domain. The cohesin-dockerin interaction...
2 KB (157 words) - 06:44, 29 October 2023
control. The cohesin complex is responsible for keeping together sister chromatids and provides binding sites for spindle attachment. Cohesin is loaded onto...
25 KB (2,857 words) - 18:11, 18 May 2024
proteins that function in the cohesin pathway. SMC1A, SMC3 and RAD21 proteins are structural components of the cohesin ring complex. NIPBL is involved...
26 KB (3,012 words) - 19:53, 23 August 2024
humans. RAD21 protein is a structural component of the highly conserved cohesin complex consisting of RAD21, SMC1A, SMC3, and SCC3 [ STAG1 (SA1) and STAG2...
57 KB (5,500 words) - 03:35, 15 April 2024
across species and are highly enriched with CCCTC-binding factor (CTCF) and cohesin. In addition, some types of genes (such as transfer RNA genes and housekeeping...
29 KB (3,140 words) - 02:23, 5 May 2024
down the center. Unlike in mitosis, only the cohesin from the chromosome arms is degraded while the cohesin surrounding the centromere remains protected...
64 KB (7,478 words) - 23:27, 22 August 2024
Spindle checkpoint (section Cohesin: SMC proteins)
the cohesin complex suggests that this complex connects directly both sister chromatids. In this proposed structure, the SMC components of cohesin play...
73 KB (9,145 words) - 07:11, 31 August 2024
The destruction of securin unleashes separase which then breaks down cohesin, a protein responsible for holding sister chromatids together. At this...
6 KB (719 words) - 02:00, 2 May 2024
Scc2 and Scc4. Cohesin interacts with the chromatin at specific loci. High levels of cohesin binding are observed at the centromere. Cohesin is also loaded...
18 KB (2,292 words) - 09:34, 3 December 2023