The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly...
14 KB (1,845 words) - 01:07, 28 March 2024
full knowledge of the mechanisms that control corticogenesis. The Reelin-DAB1 pathway is a well-defined pathway involved in corticogenesis. Cajal-Retzius...
23 KB (2,929 words) - 07:32, 15 June 2024
that the mouse disabled homologue 1 (Dab1) gene is responsible for the phenotypes of these mutant mice, as Dab1 protein was absent (yotari) or only barely...
140 KB (15,028 words) - 06:28, 5 August 2024
type of amusement ride Scrambler mouse, a mouse mutant lacking a functional DAB1 gene CJ-8 Scrambler, a Jeep CJ variant produced from 1978 to 1983 SC/Rambler...
747 bytes (130 words) - 06:09, 15 June 2024
that begin with the phosphorylation of Dab1, a tyrosine kinase phosphorylated protein which is encoded by the DAB1 gene. This protein associates with the...
27 KB (3,439 words) - 10:00, 27 March 2024
Database: 52594 TSA: 18427 Canis cinereoargenteus Wikidata: Q109647084 CoL: QLXB GBIF: 7484026 ITIS: 998409 ZooBank: 01FF418B-DAB1-4E43-806C-4914A81917C5...
34 KB (3,670 words) - 01:04, 12 September 2024
Scrambler is a spontaneous mouse mutant lacking a functional DAB1 gene, resulting in a phenotype resembling that seen in the reeler mouse. The strain was...
6 KB (876 words) - 19:07, 16 September 2023
HGNC:28358 Q8N465 3942 DAAM1 HGNC:18142 Q9Y4D1 3943 DAAM2 HGNC:18143 Q86T65 3944 DAB1 HGNC:2661 O75553 3945 DAB2 HGNC:2662 P98082 3946 DAB2IP HGNC:17294 Q5VWQ8...
277 KB (17 words) - 18:34, 6 October 2024
and limb ataxia with severe dysmetria in the lower extremities, mild dysmetria in the upper extremities, dysphagia, and abnormal ocular movements DAB1...
37 KB (3,004 words) - 05:19, 18 October 2024
The CRK protein participates in the Reelin signaling cascade downstream of DAB1. Adapter molecule crk is a member of an adapter protein family that binds...
24 KB (2,941 words) - 14:05, 24 January 2024