Entry inhibitors, also known as fusion inhibitors, are a class of antiviral drugs that prevent a virus from entering a cell, for example, by blocking...
9 KB (1,095 words) - 03:47, 25 December 2023
Antiviral drug (section Entry inhibitor)
places. Improved protease inhibitors are now in development. Protease inhibitors have also been seen in nature. A protease inhibitor was isolated from the...
55 KB (6,733 words) - 06:43, 13 June 2024
Management of HIV/AIDS (section Entry inhibitors)
inhibitors or INSTIs) as a "base". Entry inhibitors (or fusion inhibitors) interfere with binding, fusion and entry of HIV-1 to the host cell by blocking...
133 KB (15,784 words) - 05:42, 17 September 2024
Peptide T (category Entry inhibitors)
Peptide T is an HIV entry inhibitor discovered in 1986 by Candace Pert and Michael Ruff, a US neuroscientist and immunologist. Peptide T, and its modified...
14 KB (1,394 words) - 18:49, 22 September 2024
Non-nucleoside reverse transcriptase inhibitors (NNRTIs): delavirdine (brand name Rescriptor, no longer available) Attachment inhibitors fostemsavir (brand name Rukobia)...
8 KB (606 words) - 01:32, 26 July 2024
the surface of a CD4 cell. Post-attachment inhibitors are a subclass of HIV drugs called entry inhibitors. On March 6, 2018, the U.S. Food and Drug Administration...
10 KB (743 words) - 07:16, 31 August 2024
Simplex Entry inhibitor Dolutegravir HIV Integrase inhibitor Doravirine (Pifeltro) HIV NNRTI Edoxudine Herpes Simplex Thymidine analogue inhibitor Efavirenz...
13 KB (513 words) - 14:31, 4 May 2024
Enfuvirtide (category Entry inhibitors)
that disrupt fusion of virus and target cell are termed entry inhibitors or fusion inhibitors.[citation needed] HIV binds to the host CD4+ cell receptor...
12 KB (820 words) - 06:03, 18 March 2024
Maraviroc (category Entry inhibitors)
in safety between the maraviroc and placebo groups. Maraviroc is an entry inhibitor. Specifically, maraviroc is a negative allosteric modulator of the...
12 KB (954 words) - 13:32, 23 April 2024
catalysis of the reaction is blocked. Enzyme inhibitors may bind reversibly or irreversibly. Irreversible inhibitors form a chemical bond with the enzyme such...
104 KB (11,579 words) - 19:29, 18 September 2024